Nigeria torch bearers, Enyimba will on Wednesday face Congolese side Club Athletique Renaissance Aiglons (CARA) at Stade Alphonse Massamba Debat away in Brazzaville.
Congo scored in stoppage time to snatch a 1-1 draw away to Botswana on Saturday in Gaborone.
Record Ethiopian champions, Saint George, registered a win 1-0 triumph over Congolese side CARA in their 2nd 1/16th round first leg on Saturday at the Addis Ababa Stadium.
A delegation of players and officials of Asante Kotoko left Ghana on Monday morning for Congo ahead of their preliminary round second leg clash against CARA of Congo on Wednesday, 21 February 2018 in Brazzaville.
DR Congo giants, AS Vita, made the most of their home advantage when they thumped visiting Malawi champions, Be Forward Wanderers, 4-0 in the preliminary round first-leg match played at a packed Omnisports Stade des Matyrs in Kinshasa on Sunday.
A 93rd minute penalty goal by substitute Yakubu Mohamed gave Ghana’s Asante Kotoko a narrow win over visiting CARA of Congo on Sunday in Kumasi.
Libya booked their place at the last four after beating Congo 5-3 on penalties in their quarter-final clash on Sunday in Agadir
Start List: Congo vs Libya
Angola played out a barren draw against Congo in a Group D clash on Wednesday in Agadir, as the two sides progressed to the knockout stage.
Second half goals from defender Carof Bakoua and substitute Kader Bidimbou inspired Congo to a 2-0 win over Burkina Faso on Saturday in Agadir and confirm their place at the knockout stage.