The First Leg of the Additional 2nd Preliminary Round of the TotalEnergies CAF Confederation Cup 2021/22 will be played on Sunday 28 November 2021 across the continent.
Following are the fixtures (kickoff in GMT)
Sunday 28 November 2021
| Time (GMT) | Venue | Match |
|---|---|---|
| 12:00 | Nyayo National Stadium – Nairobi | Tusker (Kenya) – CS Sfaxien (Tunisia) |
| 13:00 | Heroes National Stadium – Lusaka | Zanaco (Zambia) – Binga (Mali) |
| 13:00 | National Stadium – Dar es Salaam | Simba (Tanzania) – Red Arrows (Zambia) |
| 13:00 | Stade Regional de Kigali – Kigali | APR (Rwanda) – RS Berkane (Morocco) |
| 13:00 | Mavuso Stadium – Manzini | Royal Leopards (Eswatini) – JS Kabylie (Algeria) |
| 14:00 | Stade TP Mazembe – Lubumbashi | TP Mazembe (DR Congo) – Marumo Gallants (South Africa) |
| 14:30 | Stade Alphonse Massamba Debat – Brazzaville | AS Otoho (Congo) – Gor Mahia (Kenya) |
| 15:00 | Accra Sports Stadium - Accra | Hearts of Oak (Ghana) – JS Saoura (Algeria) |
| 15:00 | Enyimba International Stadium – Aba | Rivers United (Nigeria) – Al Masry (Egypt) |
| 15:00 | Stade des Martyrs – Kinshasa | AS Maniema Union (DR Congo) – Pyramids (Egypt) |
| 15:30 | Stade General Senyi Kountche – Niamey | Gendarmerie Nationale (Niger) – DC Motema Pembe (DR Congo) |
| 16:00 | Stade Robert Chambroux – Abidjan | ASEC Mimosas (Cote d’Ivoire) – GD Interclube (Angola) |
| 16:00 | Complexe Olympique – Nouakchott | Nouadhibou (Mauritania) – Coton Sport (Cameroon) |
| 16:00 | Stade Modibo Keita – Bamako | Stade Malien (Mali) – Ahly Tripoli (Libya) |
| 16:00 | Samuel Kayon Doe Sports complex – Paynesville | LPRC Oilers (Liberia) – Orlando Pirates (South Africa) |
| 18:00 | Stade Mustapha Ben Jannet – Monastir (Tunisia) | Al Ittihad (Libya) – Ebyimba (Nigeria) |
